| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Ligand | BDBM36878 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) |
|---|
| IC50 | >1222±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 63033.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101591 |
|---|
| Residue: | 556 |
|---|
| Sequence: | MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
|
|
|
|---|
| BDBM36878 |
|---|
| n/a |
|---|
| Name | BDBM36878 |
|---|
| Synonyms: | 2-[4-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-1-piperazinyl]-1,3-benzothiazole | 2-[4-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]-1,3-benzothiazole | 2-[4-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperazino]-1,3-benzothiazole | 7-(4-Benzothiazol-2-yl-piperazin-1-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine | MLS000029982 | SMR000007687 | cid_655948 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H17N7S |
|---|
| Mol. Mass. | 351.429 |
|---|
| SMILES | Cc1cc(N2CCN(CC2)c2nc3ccccc3s2)n2ncnc2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
