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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) | ||
| Ligand | BDBM50130852 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) | ||
| IC50 | >1222±n/a nM | ||
| Citation |  PubChem, PC Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) | |||
| Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) | ||
| Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 63033.59 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | EBI_101591 | ||
| Residue: | 556 | ||
| Sequence: |
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| BDBM50130852 | |||
| n/a | |||
| Name | BDBM50130852 | ||
| Synonyms: | (vinblastine) methyl 12-ethyl-4-[17-ethyl-17-hydroxy-13-methyloxycarbonyl-(13S,15R,17S)-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-11-methylcarbonyloxy-(10S,11R,12R)-8,16-diazapentac sulfuric acid | CHEMBL378544 | Vinblastin sulfate | Vinblastine sulfate | cid_5388983 | methyl 12-ethyl-4-[17-ethyl-17-hydroxy-13-methyloxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-11-methylcarbonyloxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadecamethyl12-ethyl-4-[17-ethyl-17-hydroxy-13-methyloxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-11-methylcarbonyloxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca; sulphate | vinblastine sulphate | ||
| Type | Small organic molecule | ||
| Emp. Form. | C46H58N4O9 | ||
| Mol. Mass. | 810.9741 | ||
| SMILES | CC[C@]1(O)CC2C[N@@](C1)CCc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC |c:48| | ||
| Structure | 
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