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TargetNuclear receptor ROR-alpha
LigandBDBM39017
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA)
IC50 29040±n/a nM
Citation PubChem PC Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) PubChem Bioassay (2007)[AID]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Nuclear receptor ROR-alpha
Name:Nuclear receptor ROR-alpha
Synonyms:Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha).
Type:PROTEIN
Mol. Mass.:63033.59
Organism:Homo sapiens (Human)
Description:EBI_101591
Residue:556
Sequence:
MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
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  Blast E-value cutoff:
BDBM39017
n/a
NameBDBM39017
Synonyms:(E)-3-[4-(dimethylamino)anilino]-1-phenyl-2-propen-1-one | (E)-3-[4-(dimethylamino)anilino]-1-phenyl-prop-2-en-1-one | (E)-3-[4-(dimethylamino)anilino]-1-phenylprop-2-en-1-one | (E)-3-[[4-(dimethylamino)phenyl]amino]-1-phenyl-prop-2-en-1-one | 3-{[4-(dimethylamino)phenyl]amino}-1-phenyl-2-propen-1-one | MLS000088290 | SMR000072535 | cid_2188632
TypeSmall organic molecule
Emp. Form.C17H18N2O
Mol. Mass.266.3376
SMILESCN(C)c1ccc(cc1)N=CCC(=O)c1ccccc1 |w:9.9|
Structure
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