| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Ligand | BDBM38935 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA) |
|---|
| IC50 | <5.03±n/a nM |
|---|
| Citation |  PubChem, PC Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 63033.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101591 |
|---|
| Residue: | 556 |
|---|
| Sequence: | MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
|
|
|
|---|
| BDBM38935 |
|---|
| n/a |
|---|
| Name | BDBM38935 |
|---|
| Synonyms: | 2-(1-ethyl-2-methyl-5-benzimidazolyl)-5H-[1,2,4]triazolo[5,1-a]isoindole | 2-(1-ethyl-2-methyl-benzimidazol-5-yl)-5H-[1,2,4]triazol[5,1-a]isoindole | 2-(1-ethyl-2-methyl-benzimidazol-5-yl)-5H-[1,2,4]triazolo[5,1-a]isoindole | 2-(1-ethyl-2-methylbenzimidazol-5-yl)-5H-[1,2,4]triazolo[5,1-a]isoindole | MLS000054270 | SMR000066223 | cid_2347892 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H17N5 |
|---|
| Mol. Mass. | 315.3718 |
|---|
| SMILES | CCn1c(C)nc2cc(ccc12)-c1nc2-c3ccccc3Cn2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
