| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
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| Ligand | BDBM39152 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 |
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| IC50 | 1640±200 nM |
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| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-related protein A1 |
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| Name: | Bcl-2-related protein A1 |
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| Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
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| Type: | Apoptosis regulator protein |
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| Mol. Mass.: | 19909.74 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | gi_11024684 |
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| Residue: | 172 |
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| Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
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| BDBM39152 |
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| n/a |
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| Name | BDBM39152 |
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| Synonyms: | 3-(4-benzylpiperazin-1-yl)-4-chloro-1-(3,4-dichlorophenyl)pyrrole-2,5-dione | 3-(4-benzylpiperazino)-4-chloro-1-(3,4-dichlorophenyl)-3-pyrroline-2,5-quinone | 3-chloranyl-1-(3,4-dichlorophenyl)-4-[4-(phenylmethyl)piperazin-1-yl]pyrrole-2,5-dione | 3-chloro-1-(3,4-dichlorophenyl)-4-(4-benzylpiperazin-1-yl)-1H-pyrrole-2,5-dione | 3-chloro-1-(3,4-dichlorophenyl)-4-[4-(phenylmethyl)-1-piperazinyl]pyrrole-2,5-dione | CHEMBL1272313 | MLS-0090866.0001 | cid_16654662 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18Cl3N3O2 |
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| Mol. Mass. | 450.746 |
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| SMILES | ClC1=C(N2CCN(Cc3ccccc3)CC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:1| |
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| Structure | 
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