| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Ligand | BDBM37726 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) |
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| EC50 | >1222±n/a nM |
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| Citation |  PubChem, PC Counterscreen for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63033.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101591 |
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| Residue: | 556 |
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| Sequence: | MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
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| BDBM37726 |
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| n/a |
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| Name | BDBM37726 |
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| Synonyms: | 1-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-1,3-thiazol-5-yl]ethanone | 1-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-5-thiazolyl]ethanone | 1-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-thiazol-5-yl]ethanone | 1-{2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-1,3-thiazol-5-yl}ethanone | MLS000045468 | SMR000027225 | cid_3241407 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13N3O2S2 |
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| Mol. Mass. | 319.402 |
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| SMILES | COc1ccc2nc(Nc3nc(C)c(s3)C(C)=O)sc2c1 |
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| Structure | 
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