| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Ligand | BDBM39477 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) |
|---|
| EC50 | 636±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
|---|
| Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 63033.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101591 |
|---|
| Residue: | 556 |
|---|
| Sequence: | MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
|
|
|
|---|
| BDBM39477 |
|---|
| n/a |
|---|
| Name | BDBM39477 |
|---|
| Synonyms: | 4-[4-[(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)carbamoyl]phenyl]sulfonylpiperazine-1-carboxylic acid ethyl ester | 4-[4-[[(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)amino]-oxomethyl]phenyl]sulfonyl-1-piperazinecarboxylic acid ethyl ester | MLS000087903 | SMR000024222 | cid_3242290 | ethyl 4-[(4-{[(3-cyano-5,6-dihydro-4H-cyclopenta[b]thien-2-yl)amino]carbonyl}phenyl)sulfonyl]piperazine-1-carboxylate | ethyl 4-[4-[(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)carbamoyl]phenyl]sulfonylpiperazine-1-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H24N4O5S2 |
|---|
| Mol. Mass. | 488.58 |
|---|
| SMILES | CCOC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(=O)Nc1sc2CCCc2c1C#N |
|---|
| Structure | 
|
|---|
Search and Browse
