| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, germ cell type |
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| Ligand | BDBM34392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase |
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| IC50 | 3110±140 nM |
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| Citation |  PubChem, PC Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Alkaline phosphatase, germ cell type |
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| Name: | Alkaline phosphatase, germ cell type |
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| Synonyms: | ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57374.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_29964 |
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| Residue: | 532 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLG
DGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLC
GVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDY
SQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRD
STLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERA
GQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVL
KDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHV
MAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
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| BDBM34392 |
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| n/a |
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| Name | BDBM34392 |
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| Synonyms: | 5-[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanyl-2-propan-2-yl-2H-imidazo[1,2-c]quinazolin-3-one | 5-[2-[3,4-bis(oxidanyl)phenyl]-2-oxidanylidene-ethyl]sulfanyl-2-propan-2-yl-2H-imidazo[1,2-c]quinazolin-3-one | 5-[[2-(3,4-dihydroxyphenyl)-2-keto-ethyl]thio]-2-isopropyl-2H-imidazo[1,2-c]quinazolin-3-one | 5-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-2-propan-2-yl-2H-imidazo[1,2-c]quinazolin-3-one | 5-{[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio}-2-isopropylimidazo[1,2-c]quinazolin-3(2H)-one | MLS000094866 | SMR000030419 | cid_3242486 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19N3O4S |
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| Mol. Mass. | 409.458 |
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| SMILES | CC(C)C1N=C2N(C1=O)C(SCC(=O)c1ccc(O)c(O)c1)=Nc1ccccc21 |c:4,23| |
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| Structure | 
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