| Reaction Details |
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 | Report a problem with these data |
| Target | Steroidogenic factor 1 |
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| Ligand | BDBM39537 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) |
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| EC50 | 257±n/a nM |
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| Citation |  PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Steroidogenic factor 1 |
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| Name: | Steroidogenic factor 1 |
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| Synonyms: | AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP |
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| Type: | Nuclear Hormone Receptor |
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| Mol. Mass.: | 51643.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 461 |
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| Sequence: | MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
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| BDBM39537 |
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| n/a |
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| Name | BDBM39537 |
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| Synonyms: | MLS000077996 | N-[5-(1-adamantyl)-1,3,4-thiadiazol-2-yl]-2-furamide | N-[5-(1-adamantyl)-1,3,4-thiadiazol-2-yl]-2-furancarboxamide | N-[5-(1-adamantyl)-1,3,4-thiadiazol-2-yl]furan-2-carboxamide | SMR000018313 | cid_663488 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19N3O2S |
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| Mol. Mass. | 329.417 |
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| SMILES | [H]C12CC3([H])CC([H])(C1)CC(C2)(C3)c1nnc(NC(=O)c2ccco2)s1 |TLB:5:3:11:6.9.8,THB:2:3:9:1.11.8,2:1:9:3.12.5,5:6:11:3.12.2| |
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| Structure | 
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