Ki Summary

Reaction Details

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Target

14-3-3 protein gamma

Ligand

BDBM32017

Substrate/Competitor

n/a

Meas. Tech.

14-3-3 protein interaction modulators Dose Response Confirmation

IC50

<781.25±n/a nM

Citation

PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay(2007)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

14-3-3 protein gamma

Name:

14-3-3 protein gamma

Synonyms:

1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide

Type:

Enzyme Catalytic Domain

Mol. Mass.:

28289.17

Organism:

Homo sapiens (Human)

Description:

gi_21464101

Residue:

247

Sequence:

MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW
RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK
VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS
VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD
DGGEGNN

BDBM32017

n/a

Name

BDBM32017

Synonyms:

(7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethanoyl-4-methoxy-6,9,11-tris(oxidanyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone;hydrochloride | (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | (7S,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | DAUNORUBICIN HYDROCHLORIDE | Daunorubicin | MLS000069508 | SMR000058559 | cid_62770

Type

Small organic molecule

Emp. Form.

C27H29NO10

Mol. Mass.

527.5199

SMILES

COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O

Structure