| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 14-3-3 protein gamma |
|---|
| Ligand | BDBM32020 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | 14-3-3 protein interaction modulators Dose Response Confirmation |
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| IC50 | >50000±n/a nM |
|---|
| Citation |  PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 14-3-3 protein gamma |
|---|
| Name: | 14-3-3 protein gamma |
|---|
| Synonyms: | 1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 28289.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21464101 |
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| Residue: | 247 |
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| Sequence: | MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW
RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK
VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS
VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD
DGGEGNN
|
|
|
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| BDBM32020 |
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| n/a |
|---|
| Name | BDBM32020 |
|---|
| Synonyms: | 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol | 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol | 4-[4-[3,4-bis(oxidanyl)phenyl]-2,3-dimethyl-butyl]benzene-1,2-diol | BDBM166684 | CHEMBL52 | LOX inhibitor, N/A | MLS000069451 | NORDIHYDROGUAIARETIC ACID | Nordihydroguaiaretic acid (NDGA) | SMR000059049 | US10857082, Compound 2.18 | cid_4534 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C18H22O4 |
|---|
| Mol. Mass. | 302.3649 |
|---|
| SMILES | CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 |
|---|
| Structure | 
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|---|
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