| Reaction Details |
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 | Report a problem with these data |
| Target | 14-3-3 protein gamma |
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| Ligand | BDBM32120 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | 14-3-3 protein interaction modulators Dose Response Confirmation |
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| IC50 | 10660.4±n/a nM |
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| Citation |  PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| 14-3-3 protein gamma |
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| Name: | 14-3-3 protein gamma |
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| Synonyms: | 1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 28289.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21464101 |
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| Residue: | 247 |
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| Sequence: | MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW
RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK
VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS
VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD
DGGEGNN
|
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|
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| BDBM32120 |
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| n/a |
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| Name | BDBM32120 |
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| Synonyms: | 2-[[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfinyl]-N-(pyridin-2-ylmethyl)acetamide | 2-[[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfinyl]-N-(pyridin-2-ylmethyl)ethanamide | 2-[[2-(4-methoxyphenyl)-5-methyl-4-oxazolyl]methylsulfinyl]-N-(2-pyridinylmethyl)acetamide | 2-[[2-(4-methoxyphenyl)-5-methyl-oxazol-4-yl]methylsulfinyl]-N-(2-pyridylmethyl)acetamide | MLS000117623 | SMR000094571 | cid_5308158 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O4S |
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| Mol. Mass. | 399.463 |
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| SMILES | COc1ccc(cc1)-c1nc(CS(=O)CC(=O)NCc2ccccn2)c(C)o1 |
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| Structure | 
|
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