| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase BAP1 |
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| Ligand | BDBM40294 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | BAP1 Enzyme inhibitors Dose Response Confirmation |
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| IC50 | >50000±n/a nM |
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| Citation |  PubChem, PC BAP1 Enzyme inhibitors Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ubiquitin carboxyl-terminal hydrolase BAP1 |
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| Name: | Ubiquitin carboxyl-terminal hydrolase BAP1 |
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| Synonyms: | BAP1 | BAP1_HUMAN | KIAA0272 | Ubiquitin carboxyl-terminal hydrolase BAP1 (BRCA1-associated protein 1) (Cerebral protein 6). |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 80364.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_68565074 |
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| Residue: | 729 |
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| Sequence: | MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR
KVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK
GFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK
YEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR
APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG
KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT
HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR
VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE
KEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF
KIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR
SRPYKAKRQ
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| BDBM40294 |
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| n/a |
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| Name | BDBM40294 |
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| Synonyms: | 3-(3-chloranyl-4-methyl-phenyl)-8-(3,4-dimethoxyphenyl)-6-oxidanylidene-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | 3-(3-chloro-4-methyl-phenyl)-8-(3,4-dimethoxyphenyl)-6-keto-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | 3-(3-chloro-4-methylphenyl)-8-(3,4-dimethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | MLS000117236 | SMR000094189 | cid_5307404 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22ClN3O3S |
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| Mol. Mass. | 455.957 |
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| SMILES | COc1ccc(cc1OC)C1CC(=O)N2CN(CSC2=C1C#N)c1ccc(C)c(Cl)c1 |c:21| |
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| Structure | 
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