| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mothers against decapentaplegic homolog 3 |
|---|
| Ligand | BDBM31698 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SMAD Transcription Factor Inhibitors Dose Response Confirmation |
|---|
| IC50 | 14050±n/a nM |
|---|
| Citation |  PubChem, PC SMAD Transcription Factor Inhibitors Dose Response Confirmation PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mothers against decapentaplegic homolog 3 |
|---|
| Name: | Mothers against decapentaplegic homolog 3 |
|---|
| Synonyms: | MADH3 | SMAD3 | SMAD3_HUMAN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48085.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_5174513 |
|---|
| Residue: | 425 |
|---|
| Sequence: | MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
CSSVS
|
|
|
|---|
| BDBM31698 |
|---|
| n/a |
|---|
| Name | BDBM31698 |
|---|
| Synonyms: | 3-bromanyl-5-(3,3-dimethylpiperidin-1-yl)carbonyl-pyran-2-one | 3-bromo-5-(3,3-dimethylpiperidine-1-carbonyl)pyran-2-one | 3-bromo-5-[(3,3-dimethyl-1-piperidinyl)-oxomethyl]-2-pyranone | MLS000080954 | SMR000044848 | cid_664033 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H16BrNO3 |
|---|
| Mol. Mass. | 314.175 |
|---|
| SMILES | CC1(C)CCCN(C1)C(=O)c1coc(=O)c(Br)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
