| Reaction Details |
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 | Report a problem with these data |
| Target | Mothers against decapentaplegic homolog 3 |
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| Ligand | BDBM39886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SMAD Transcription Factor Inhibitors Dose Response Confirmation |
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| IC50 | 2729±n/a nM |
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| Citation |  PubChem, PC SMAD Transcription Factor Inhibitors Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mothers against decapentaplegic homolog 3 |
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| Name: | Mothers against decapentaplegic homolog 3 |
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| Synonyms: | MADH3 | SMAD3 | SMAD3_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48085.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5174513 |
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| Residue: | 425 |
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| Sequence: | MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
CSSVS
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| BDBM39886 |
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| n/a |
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| Name | BDBM39886 |
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| Synonyms: | 4b,9b-bis(oxidanyl)-7,8-dihydro-6H-indeno[1,2-b][1]benzofuran-9,10-dione | 4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b][1]benzofuran-9,10-dione | 4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b]benzofuran-9,10-dione | 4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b]benzofuran-9,10-quinone | MLS000104338 | SMR000054273 | cid_2834991 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12O5 |
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| Mol. Mass. | 272.2528 |
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| SMILES | OC12OC3=C(C(=O)CCC3)C1(O)C(=O)c1ccccc21 |t:3| |
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| Structure | 
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