| Reaction Details |
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 | Report a problem with these data |
| Target | Mothers against decapentaplegic homolog 3 |
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| Ligand | BDBM40319 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SMAD Transcription Factor Inhibitors Dose Response Confirmation |
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| IC50 | 2815±n/a nM |
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| Citation |  PubChem, PC SMAD Transcription Factor Inhibitors Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mothers against decapentaplegic homolog 3 |
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| Name: | Mothers against decapentaplegic homolog 3 |
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| Synonyms: | MADH3 | SMAD3 | SMAD3_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48085.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5174513 |
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| Residue: | 425 |
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| Sequence: | MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
CSSVS
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| BDBM40319 |
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| n/a |
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| Name | BDBM40319 |
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| Synonyms: | 4-[(3,4-diketo-1-naphthyl)amino]benzoic acid ethyl ester | 4-[(3,4-dioxo-1-naphthalenyl)amino]benzoic acid ethyl ester | MLS000519473 | SMR000129892 | cid_691731 | ethyl 4-[(3,4-dioxonaphthalen-1-yl)amino]benzoate | ethyl 4-[[3,4-bis(oxidanylidene)naphthalen-1-yl]amino]benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15NO4 |
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| Mol. Mass. | 321.3267 |
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| SMILES | CCOC(=O)c1ccc(NC2=CC(=O)C(=O)c3ccccc23)cc1 |t:10| |
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| Structure | 
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