| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor XII |
|---|
| Ligand | BDBM40378 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Factor XIIa Dose Response Confirmation |
|---|
| IC50 | >50000±0 nM |
|---|
| Citation |  PubChem, PC Factor XIIa Dose Response Confirmation PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Coagulation factor XII |
|---|
| Name: | Coagulation factor XII |
|---|
| Synonyms: | Beta-factor XIIa part 1 | Beta-factor XIIa part 2 | Carboxylesterase 2 (intestine, liver) | Coagulation factor XII | Coagulation factor XII (FXII) | Coagulation factor XIIa heavy chain | Coagulation factor XIIa light chain | F12 | FA12_HUMAN | Factor XIIa | Factor XIIa (fXIIa) | HAF | Hageman factor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 67810.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00748 |
|---|
| Residue: | 615 |
|---|
| Sequence: | MRALLLLGFLLVSLESTLSIPPWEAPKEHKYKAEEHTVVLTVTGEPCHFPFQYHRQLYHK
CTHKGRPGPQPWCATTPNFDQDQRWGYCLEPKKVKDHCSKHSPCQKGGTCVNMPSGPHCL
CPQHLTGNHCQKEKCFEPQLLRFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQACRT
NPCLHGGRCLEVEGHRLCHCPVGYTGAFCDVDTKASCYDGRGLSYRGLARTTLSGAPCQP
WASEATYRNVTAEQARNWGLGGHAFCRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQTPTQ
AAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCG
QRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAP
EDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSP
YVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS
SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYT
DVAYYLAWIREHTVS
|
|
|
|---|
| BDBM40378 |
|---|
| n/a |
|---|
| Name | BDBM40378 |
|---|
| Synonyms: | 3-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(2-furylmethyl)propanamide | 3-(2,3-dihydro-1,4-benzodioxin-3-yl)-N-(2-furanylmethyl)propanamide | 3-(2,3-dihydro-1,4-benzodioxin-3-yl)-N-(2-furfuryl)propionamide | 3-(2,3-dihydro-1,4-benzodioxin-3-yl)-N-(furan-2-ylmethyl)propanamide | MLS000065376 | SMR000079140 | cid_2965121 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H17NO4 |
|---|
| Mol. Mass. | 287.3105 |
|---|
| SMILES | O=C(CCC1COc2ccccc2O1)NCc1ccco1 |
|---|
| Structure | 
|
|---|
Search and Browse
