| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Heat shock 70 kDa protein 1A |
|---|
| Ligand | BDBM31692 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 |
|---|
| IC50 | >100000±0 nM |
|---|
| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Heat shock 70 kDa protein 1A |
|---|
| Name: | Heat shock 70 kDa protein 1A |
|---|
| Synonyms: | HSPA1A | Heat Shock 70kDa Protein 1 | V9GZ37_HUMAN | heat shock 70kDa protein 1A |
|---|
| Type: | ATP-binding protein |
|---|
| Mol. Mass.: | 51937.99 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_123271505; GST-tagged ATPase domain |
|---|
| Residue: | 476 |
|---|
| Sequence: | MAKAAAIGIDLGTTYSCVGVFQHGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGD
THLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEID
SLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPK
VQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLET
AGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIP
PAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKY
KAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANT
LAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
|
|
|
|---|
| BDBM31692 |
|---|
| n/a |
|---|
| Name | BDBM31692 |
|---|
| Synonyms: | 4-[(1-tert-butyl-1,2,3,4-tetrazol-5-yl)-quinolin-6-yl-methyl]thiomorpholine | 4-[(1-tert-butyl-5-tetrazolyl)-(6-quinolinyl)methyl]thiomorpholine | 4-[(1-tert-butyltetrazol-5-yl)-(6-quinolyl)methyl]thiomorpholine | 4-[(1-tert-butyltetrazol-5-yl)-quinolin-6-ylmethyl]thiomorpholine | 6-[(1-tert-Butyl-1H-tetrazol-5-yl)-thiomorpholin-4-yl-methyl]-quinoline | MLS000075443 | SMR000003972 | cid_651602 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N6S |
|---|
| Mol. Mass. | 368.499 |
|---|
| SMILES | CC(C)(C)n1nnnc1C(N1CCSCC1)c1ccc2ncccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
