| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock 70 kDa protein 1A |
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| Ligand | BDBM31716 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 |
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| IC50 | 12400±1120 nM |
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| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock 70 kDa protein 1A |
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| Name: | Heat shock 70 kDa protein 1A |
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| Synonyms: | HSPA1A | Heat Shock 70kDa Protein 1 | V9GZ37_HUMAN | heat shock 70kDa protein 1A |
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| Type: | ATP-binding protein |
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| Mol. Mass.: | 51937.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_123271505; GST-tagged ATPase domain |
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| Residue: | 476 |
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| Sequence: | MAKAAAIGIDLGTTYSCVGVFQHGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGD
THLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEID
SLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPK
VQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLET
AGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIP
PAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKY
KAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANT
LAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
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| BDBM31716 |
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| n/a |
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| Name | BDBM31716 |
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| Synonyms: | 4-methylbenzoic acid (4-salicyloylazoanilino) ester | 4-methylbenzoic acid [4-[(2-hydroxyphenyl)-oxomethyl]azoanilino] ester | MLS000521412 | SMR000131820 | [4-[(2-hydroxybenzoyl)diazenyl]anilino] 4-methylbenzoate | [[4-[(2-hydroxyphenyl)carbonyldiazenyl]phenyl]amino] 4-methylbenzoate | cid_4483669 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17N3O4 |
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| Mol. Mass. | 375.3774 |
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| SMILES | Cc1ccc(cc1)C(=O)ONc1ccc(cc1)\N=N\C(=O)c1ccccc1O |
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| Structure | 
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