| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin S |
|---|
| Ligand | BDBM32061 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cathepsin S dose-response confirmation |
|---|
| IC50 | 450.965±29.435 nM |
|---|
| Citation |  PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Cathepsin S |
|---|
| Name: | Cathepsin S |
|---|
| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 37507.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P25774 |
|---|
| Residue: | 331 |
|---|
| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
|
|
|
|---|
| BDBM32061 |
|---|
| n/a |
|---|
| Name | BDBM32061 |
|---|
| Synonyms: | 1,8-bis(azanyl)-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-3,6-bis(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-3,6-dipyrrolidino-2,7-naphthyridine-4-carbonitrile | MLS000054131 | SMR000061605 | cid_2997948 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H21N7 |
|---|
| Mol. Mass. | 323.3955 |
|---|
| SMILES | Nc1nc(cc2c(C#N)c(nc(N)c12)N1CCCC1)N1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
