Reaction Details | |||
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Report a problem with these data | |||
Target | P2X purinoceptor 3 | ||
Ligand | BDBM266955 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Human P2X3 Receptor Inhibition Assay | ||
pH | 7.5±n/a | ||
IC50 | 1.000±n/a nM | ||
Comments | extracted | ||
Citation | Kai, H; Horiguchi, T; Asahi, K; Fujii, Y Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same US Patent US9718790 Publication Date 8/1/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
P2X purinoceptor 3 | |||
Name: | P2X purinoceptor 3 | ||
Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa | ||
Type: | Protein | ||
Mol. Mass.: | 44292.02 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P56373 | ||
Residue: | 397 | ||
Sequence: |
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BDBM266955 | |||
n/a | |||
Name | BDBM266955 | ||
Synonyms: | US9718790, I-2701 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H30N6O5 | ||
Mol. Mass. | 494.5429 | ||
SMILES | CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccc(nn3)C(=O)OC)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O |r,wU:27.28,wD:30.32,(6,-1.15,;4.67,-.38,;3.33,-1.15,;2,-.38,;2,1.15,;.67,-1.15,;.67,-2.69,;-.67,-3.47,;-2,-2.69,;-3.33,-3.47,;-4.67,-2.69,;-4.67,-1.15,;-6,-.38,;-6,1.15,;-7.34,1.93,;-7.34,3.47,;-6,4.23,;-4.67,3.47,;-4.67,1.93,;-6,5.78,;-7.34,6.54,;-4.67,6.54,;-4.67,8.08,;-3.33,-.38,;-2,-1.15,;2,-3.47,;2,-5,;3.33,-5.78,;4.67,-5,;6,-5.78,;6,-7.31,;7.34,-8.08,;4.67,-8.08,;3.33,-7.31,;3.33,-2.69,;4.67,-3.47,)| | ||
Structure |