Ki Summary

Reaction Details

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Target

Sphingosine 1-phosphate receptor 2

Ligand

BDBM41675

Substrate/Competitor

n/a

Meas. Tech.

Dose Response Cell Based Assay for Agonists of the S1P2 Receptor

EC50

1691±n/a nM

Citation

PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor PubChem Bioassay(2007)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Sphingosine 1-phosphate receptor 2

Name:

Sphingosine 1-phosphate receptor 2

Synonyms:

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

38883.16

Organism:

Homo sapiens (Human)

Description:

Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.

Residue:

353

Sequence:

MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV

BDBM41675

n/a

Name

BDBM41675

Synonyms:

2-Amino-1-benzo[1,3]dioxol-5-ylmethyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylic acid (3-methyl-butyl)-amide | 2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-(3-methylbutyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-(3-methylbutyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-isoamyl-1-piperonyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-azanyl-1-(1,3-benzodioxol-5-ylmethyl)-N-(3-methylbutyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000558485 | SMR000149001 | cid_1891819

Type

Small organic molecule

Emp. Form.

C24H25N5O3

Mol. Mass.

431.487

SMILES

CC(C)CCNC(=O)c1c(N)n(Cc2ccc3OCOc3c2)c2nc3ccccc3nc12

Structure