Ki Summary

Reaction Details

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Target

Sphingosine 1-phosphate receptor 2

Ligand

BDBM41676

Substrate/Competitor

n/a

Meas. Tech.

Dose Response Cell Based Assay for Agonists of the S1P2 Receptor

EC50

2199±n/a nM

Citation

PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor PubChem Bioassay(2007)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Sphingosine 1-phosphate receptor 2

Name:

Sphingosine 1-phosphate receptor 2

Synonyms:

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

38883.16

Organism:

Homo sapiens (Human)

Description:

Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.

Residue:

353

Sequence:

MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV

BDBM41676

n/a

Name

BDBM41676

Synonyms:

2-Amino-1-thiophen-2-ylmethyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylic acid (3-phenyl-propyl)-amide | 2-amino-N-(3-phenylpropyl)-1-(2-thenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-(3-phenylpropyl)-1-(thiophen-2-ylmethyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-amino-N-(3-phenylpropyl)-1-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-azanyl-N-(3-phenylpropyl)-1-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000557937 | SMR000148653 | cid_2016176

Type

Small organic molecule

Emp. Form.

C25H23N5OS

Mol. Mass.

441.548

SMILES

Nc1c(C(=O)NCCCc2ccccc2)c2nc3ccccc3nc2n1Cc1cccs1

Structure