Reaction Details |
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Target | Bcl-2-related protein A1 |
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Ligand | BDBM31067 |
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Substrate/Competitor | n/a |
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Meas. Tech. | In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study |
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IC50 | 23200±3920 nM |
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Citation | PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Bcl-2-related protein A1 |
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Name: | Bcl-2-related protein A1 |
Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
Type: | Apoptosis regulator protein |
Mol. Mass.: | 19909.74 |
Organism: | Mus musculus (Mouse) |
Description: | gi_11024684 |
Residue: | 172 |
Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
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BDBM31067 |
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n/a |
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Name | BDBM31067 |
Synonyms: | 4-(3,4-dimethoxyphenyl)-2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidine | 4-(3,4-dimethoxyphenyl)-2-mesyl-6-(trifluoromethyl)pyrimidine | 4-(3,4-dimethoxyphenyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine | MLS000044648 | SMR000022592 | cid_3244140 |
Type | Small organic molecule |
Emp. Form. | C14H13F3N2O4S |
Mol. Mass. | 362.324 |
SMILES | COc1ccc(cc1OC)-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F |
Structure |
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