BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBcl-2-related protein A1
LigandBDBM39170
Substrate/Competitorn/a
Meas. Tech.In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study
IC50 8850±1660 nM
Citation PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:Apoptosis regulator protein
Mol. Mass.:19909.74
Organism:Mus musculus (Mouse)
Description:gi_11024684
Residue:172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39170
n/a
NameBDBM39170
Synonyms:3-chloranyl-4-[4-[2-(2-hydroxyethyloxy)ethyl]piperazin-1-yl]-1-(3-methoxyphenyl)pyrrole-2,5-dione | 3-chloro-4-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]-1-(3-methoxyphenyl)pyrrole-2,5-dione | 3-chloro-4-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]-1-(3-methoxyphenyl)pyrrole-2,5-dione | 3-chloro-4-[4-[2-(2-hydroxyethoxy)ethyl]piperazino]-1-(3-methoxyphenyl)-3-pyrroline-2,5-quinone | MLS-0111716.0001 | cid_16654745
TypeSmall organic molecule
Emp. Form.C19H24ClN3O5
Mol. Mass.409.864
SMILESCOc1cccc(c1)N1C(=O)C(Cl)=C(N2CCN(CCOCCO)CC2)C1=O |t:13|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: