BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBcl-2-related protein A1
LigandBDBM39185
Substrate/Competitorn/a
Meas. Tech.In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study
IC50 1700±350 nM
Citation PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:Apoptosis regulator protein
Mol. Mass.:19909.74
Organism:Mus musculus (Mouse)
Description:gi_11024684
Residue:172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39185
n/a
NameBDBM39185
Synonyms:3-chloranyl-1-(4-methylphenyl)-4-[(4-methylphenyl)amino]pyrrole-2,5-dione | 3-chloro-4-(4-methylanilino)-1-(4-methylphenyl)pyrrole-2,5-dione | 3-chloro-4-(p-toluidino)-1-(p-tolyl)-3-pyrroline-2,5-quinone | MLS-0111861.0001 | cid_728014
TypeSmall organic molecule
Emp. Form.C18H15ClN2O2
Mol. Mass.326.777
SMILESCc1ccc(cc1)N=C1C(Cl)C(=O)N(C1=O)c1ccc(C)cc1 |w:7.7|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: