Reaction Details |
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Target | Neuropeptide Y receptor type 2 |
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Ligand | BDBM42421 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism |
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IC50 | 30590±n/a nM |
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Citation | PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Neuropeptide Y receptor type 2 |
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Name: | Neuropeptide Y receptor type 2 |
Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 42734.65 |
Organism: | Homo sapiens (Human) |
Description: | NPY-Y2 NPY2R HUMAN::P49146 |
Residue: | 381 |
Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
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BDBM42421 |
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n/a |
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Name | BDBM42421 |
Synonyms: | 2-[[[2-(4-chlorophenyl)-5-methyl-3-pyrazolyl]amino]methylidene]propanedioic acid diethyl ester | 2-[[[2-(4-chlorophenyl)-5-methyl-pyrazol-3-yl]amino]methylene]malonic acid diethyl ester | MLS000541363 | SMR000126221 | cid_3849628 | diethyl 2-({[1-(4-chlorophenyl)-3-methyl-1H-pyrazol-5-yl]amino}methylene)malonate | diethyl 2-[[[2-(4-chlorophenyl)-5-methyl-pyrazol-3-yl]amino]methylidene]propanedioate | diethyl 2-[[[2-(4-chlorophenyl)-5-methylpyrazol-3-yl]amino]methylidene]propanedioate |
Type | Small organic molecule |
Emp. Form. | C18H20ClN3O4 |
Mol. Mass. | 377.822 |
SMILES | CCOC(=O)C(C=Nc1cc(C)nn1-c1ccc(Cl)cc1)C(=O)OCC |w:7.7| |
Structure |
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