| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptosis regulator Bcl-2 |
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| Ligand | BDBM33048 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2 |
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| EC50 | 760±n/a nM |
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| Citation |  PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2 PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Apoptosis regulator Bcl-2 |
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| Name: | Apoptosis regulator Bcl-2 |
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| Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
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| Type: | Homodimer or heterodimer |
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| Mol. Mass.: | 26269.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10415 |
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| Residue: | 239 |
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| Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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| BDBM33048 |
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| n/a |
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| Name | BDBM33048 |
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| Synonyms: | (5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-2,6-diketo-4-methyl-nicotinonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-3-pyridinecarbonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxopyridine-3-carbonitrile | 5-[4-(dimethylamino)phenyl]imino-4-methyl-2,6-bis(oxidanylidene)-1-(3-oxidanylpropyl)pyridine-3-carbonitrile | MLS000089998 | SMR000024616 | cid_3239318 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N4O3 |
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| Mol. Mass. | 340.3764 |
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| SMILES | CN(C)c1ccc(cc1)\N=C1/C(C)=C(C#N)C(=O)N(CCCO)C1=O |t:13| |
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| Structure | 
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