Reaction Details |
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Target | Apoptosis regulator Bcl-2 |
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Ligand | BDBM32318 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2 |
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EC50 | 670±n/a nM |
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Citation | PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2 PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Apoptosis regulator Bcl-2 |
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Name: | Apoptosis regulator Bcl-2 |
Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
Type: | Homodimer or heterodimer |
Mol. Mass.: | 26269.11 |
Organism: | Homo sapiens (Human) |
Description: | P10415 |
Residue: | 239 |
Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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BDBM32318 |
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n/a |
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Name | BDBM32318 |
Synonyms: | 4-[[4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-2-thiazolyl]amino]phenol;hydrobromide | 4-[[4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-1,3-thiazol-2-yl]amino]phenol;hydrobromide | 4-[[4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-yl]amino]phenol;hydrobromide | MLS000715643 | SMR000277160 | cid_5337459 |
Type | Small organic molecule |
Emp. Form. | C16H13N5OS |
Mol. Mass. | 323.372 |
SMILES | Cc1nc2ncccn2c1-c1csc(Nc2ccc(O)cc2)n1 |
Structure |
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