| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division control protein 42 homolog |
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| Ligand | BDBM43225 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant |
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| EC50 | 5105±n/a nM |
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| Citation |  PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cell division control protein 42 homolog |
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| Name: | Cell division control protein 42 homolog |
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| Synonyms: | CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21258.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_652970 |
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| Residue: | 191 |
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| Sequence: | MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
EPKKSRRCVLL
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| BDBM43225 |
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| n/a |
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| Name | BDBM43225 |
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| Synonyms: | 4-(4-tert-butylphenyl)-2-(4-methylphenyl)sulfanyl-4-oxidanylidene-butanoic acid | 4-(4-tert-butylphenyl)-2-(4-methylphenyl)sulfanyl-4-oxobutanoic acid | 4-(4-tert-butylphenyl)-2-[(4-methylphenyl)thio]-4-oxobutanoic acid | 4-(4-tert-butylphenyl)-4-keto-2-(p-tolylthio)butyric acid | 4-[4-(tert-butyl)phenyl]-2-[(4-methylphenyl)sulfanyl]-4-oxobutanoic acid | MLS000736261 | SMR000338511 | cid_4253856 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24O3S |
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| Mol. Mass. | 356.478 |
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| SMILES | Cc1ccc(SC(CC(=O)c2ccc(cc2)C(C)(C)C)C(O)=O)cc1 |
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| Structure | 
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