| Reaction Details |
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 | Report a problem with these data |
| Target | Ras-related protein Rab-2A |
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| Ligand | BDBM43220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype |
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| EC50 | 704.2±n/a nM |
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| Citation |  PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ras-related protein Rab-2A |
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| Name: | Ras-related protein Rab-2A |
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| Synonyms: | RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A. |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23545.28 |
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| Organism: | Canis lupus familiaris |
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| Description: | gi_46577642 |
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| Residue: | 212 |
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| Sequence: | MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
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| BDBM43220 |
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| n/a |
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| Name | BDBM43220 |
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| Synonyms: | 4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide | 4-[5-(4-methoxyphenyl)-3-phenyl-2-pyrazolin-1-yl]benzenesulfonamide | 4-[5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]benzenesulfonamide | MLS000693334 | SMR000299863 | US9388139, 11 | cid_2950007 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N3O3S |
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| Mol. Mass. | 407.485 |
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| SMILES | COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1 |c:11| |
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| Structure | 
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