| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 7 |
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| Ligand | BDBM32357 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CDK7 counterscreen of confirmed PKD inhibitors-57K library addition |
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| IC50 | >100000±n/a nM |
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| Citation |  PubChem, PC CDK7 counterscreen of confirmed PKD inhibitors-57K library addition PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cyclin-dependent kinase 7 |
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| Name: | Cyclin-dependent kinase 7 |
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| Synonyms: | 39 kDa protein kinase | CAK | CAK1 | CDK-activating kinase | CDK-activating kinase 1 (CAK) | CDK7 | CDK7_HUMAN | CDKN7 | Cell division protein kinase 7 | Cyclin-Dependent Kinase 7 (CDK7) | Cyclin-dependent kinase 7 (CDK7/cyclin H) | MO15 | P39 Mo15 | STK1 | TFIIH basal transcription factor complex kinase subunit |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 39047.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 346 |
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| Sequence: | MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG
PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
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| BDBM32357 |
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| n/a |
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| Name | BDBM32357 |
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| Synonyms: | 2-(2-furoyl)-N-p-anisyl-3,4-dihydro-1H-isoquinoline-3-carboxamide | 2-(furan-2-carbonyl)-N-[(4-methoxyphenyl)methyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide | 2-(furan-2-ylcarbonyl)-N-[(4-methoxyphenyl)methyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide | 2-[2-furanyl(oxo)methyl]-N-[(4-methoxyphenyl)methyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide | MLS000517008 | SMR000343177 | cid_3999744 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N2O4 |
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| Mol. Mass. | 390.4318 |
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| SMILES | COc1ccc(CNC(=O)C2Cc3ccccc3CN2C(=O)c2ccco2)cc1 |
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| Structure | 
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