| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase PLK1 |
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| Ligand | BDBM32343 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PLK1 counterscreening assay for identified PKD inhibitors |
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| IC50 | >50000±n/a nM |
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| Citation |  PubChem, PC PLK1 counterscreening assay for identified PKD inhibitors PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Serine/threonine-protein kinase PLK1 |
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| Name: | Serine/threonine-protein kinase PLK1 |
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| Synonyms: | PLK | PLK-1 | PLK1 | PLK1_HUMAN | Polo-like kinase 1 (PlK1) | Polo-like kinase 1 (Plk-1) | STPK13 | Serine/threonine-protein kinase (PLK1) | Serine/threonine-protein kinase 13 | polo-like kinase |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 68277.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P53350 |
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| Residue: | 603 |
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| Sequence: | MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLG
KGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFF
EDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLG
NLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCI
MYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELL
NDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEE
PVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDK
YGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLK
YFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTK
LILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRL
KAS
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| BDBM32343 |
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| n/a |
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| Name | BDBM32343 |
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| Synonyms: | (3,5-dichloro-4-pyridyl)-(4-pyridylmethyleneamino)amine | (3,5-dichloro-4-pyridyl)-[(E)-4-pyridylmethyleneamino]amine | 3,5-bis(chloranyl)-N-(pyridin-4-ylmethylideneamino)pyridin-4-amine | 3,5-dichloro-N-(pyridin-4-ylmethylideneamino)-4-pyridinamine | 3,5-dichloro-N-(pyridin-4-ylmethylideneamino)pyridin-4-amine | MLS000583434 | SMR000206620 | cid_4438738 | isonicotinaldehyde (3,5-dichloropyridin-4-yl)hydrazone |
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| Type | Small organic molecule |
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| Emp. Form. | C11H8Cl2N4 |
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| Mol. Mass. | 267.114 |
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| SMILES | Clc1cncc(Cl)c1N=NCc1ccncc1 |w:8.8| |
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| Structure | 
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