Reaction Details |
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Target | G2/mitotic-specific cyclin-B1 |
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Ligand | BDBM36923 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation |
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EC50 | >5527±n/a nM |
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Citation | PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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G2/mitotic-specific cyclin-B1 |
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Name: | G2/mitotic-specific cyclin-B1 |
Synonyms: | CCNB | CCNB1 | CCNB1_HUMAN |
Type: | Enzyme Subunit |
Mol. Mass.: | 48340.95 |
Organism: | Homo sapiens (Human) |
Description: | P14635 |
Residue: | 433 |
Sequence: | MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV
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BDBM36923 |
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n/a |
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Name | BDBM36923 |
Synonyms: | (Z)-3,4-bis(benzenesulfonyl)-2-buten-1-ol | (Z)-3,4-bis(benzenesulfonyl)but-2-en-1-ol | (Z)-3,4-bis(phenylsulfonyl)but-2-en-1-ol | (Z)-3,4-dibesylbut-2-en-1-ol | MLS000080860 | SMR000043655 | cid_5389617 |
Type | Small organic molecule |
Emp. Form. | C16H16O5S2 |
Mol. Mass. | 352.425 |
SMILES | OC\C=C(\CS(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 |
Structure |
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