Ki Summary

Reaction Details

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Target

G2/mitotic-specific cyclin-B1

Ligand

BDBM43756

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation

EC50

>49750±n/a nM

Citation

PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

G2/mitotic-specific cyclin-B1

Name:

G2/mitotic-specific cyclin-B1

Synonyms:

CCNB | CCNB1 | CCNB1_HUMAN

Type:

Enzyme Subunit

Mol. Mass.:

48340.95

Organism:

Homo sapiens (Human)

Description:

P14635

Residue:

433

Sequence:

MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV

BDBM43756

n/a

Name

BDBM43756

Synonyms:

MLS000526502 | N-Cyclohexyl-2-[(3-ethoxy-phenyl)-(2-thiophen-2-yl-acetyl)-amino]-2-(1-methyl-1H-pyrrol-2-yl)-acetamide | N-cyclohexyl-2-(3-ethoxy-N-(1-oxo-2-thiophen-2-ylethyl)anilino)-2-(1-methyl-2-pyrrolyl)acetamide | N-cyclohexyl-2-(3-ethoxy-N-(2-thiophen-2-ylacetyl)anilino)-2-(1-methylpyrrol-2-yl)acetamide | N-cyclohexyl-2-(3-ethoxy-N-[2-(2-thienyl)acetyl]anilino)-2-(1-methylpyrrol-2-yl)acetamide | N-cyclohexyl-2-[(3-ethoxyphenyl)-(2-thiophen-2-ylethanoyl)amino]-2-(1-methylpyrrol-2-yl)ethanamide | SMR000116976 | cid_3191192

Type

Small organic molecule

Emp. Form.

C27H33N3O3S

Mol. Mass.

479.634

SMILES

CCOc1cccc(c1)N(C(C(=O)NC1CCCCC1)c1cccn1C)C(=O)Cc1cccs1

Structure