Ki Summary

Reaction Details

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Target

G2/mitotic-specific cyclin-B1

Ligand

BDBM43375

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation

EC50

>1842±n/a nM

Citation

PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

G2/mitotic-specific cyclin-B1

Name:

G2/mitotic-specific cyclin-B1

Synonyms:

CCNB | CCNB1 | CCNB1_HUMAN

Type:

Enzyme Subunit

Mol. Mass.:

48340.95

Organism:

Homo sapiens (Human)

Description:

P14635

Residue:

433

Sequence:

MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV

BDBM43375

n/a

Name

BDBM43375

Synonyms:

(2E)-2-(1-cyano-2,2,2-trifluoro-ethylidene)-5-phenyl-1,3-oxathiole-4-carboxylic acid ethyl ester | (2E)-2-(1-cyano-2,2,2-trifluoroethylidene)-5-phenyl-1,3-oxathiole-4-carboxylic acid ethyl ester | 2-[1-Cyano-2,2,2-trifluoro-eth-(E)-ylidene]-5-phenyl-[1,3]oxathiole-4-carboxylic acid ethyl ester | MLS000556838 | SMR000147955 | cid_1883255 | ethyl (2E)-2-(1-cyano-2,2,2-trifluoroethylidene)-5-phenyl-1,3-oxathiole-4-carboxylate | ethyl (2E)-2-[1-cyano-2,2,2-tris(fluoranyl)ethylidene]-5-phenyl-1,3-oxathiole-4-carboxylate

Type

Small organic molecule

Emp. Form.

C15H10F3NO3S

Mol. Mass.

341.305

SMILES

CCOC(=O)C1=C(O\C(S1)=C(\C#N)C(F)(F)F)c1ccccc1 |t:5|

Structure