| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G2/mitotic-specific cyclin-B1 |
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| Ligand | BDBM43760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation |
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| EC50 | >49750±n/a nM |
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| Citation |  PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| G2/mitotic-specific cyclin-B1 |
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| Name: | G2/mitotic-specific cyclin-B1 |
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| Synonyms: | CCNB | CCNB1 | CCNB1_HUMAN |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 48340.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14635 |
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| Residue: | 433 |
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| Sequence: | MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV
|
|
|
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| BDBM43760 |
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| n/a |
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| Name | BDBM43760 |
|---|
| Synonyms: | MLS000565334 | N'-(5-bromanyl-2-oxidanylidene-indol-3-yl)-2-pyrrol-1-yl-benzohydrazide | N'-(5-bromo-2-keto-indol-3-yl)-2-pyrrol-1-yl-benzohydrazide | N'-(5-bromo-2-oxo-3-indolyl)-2-(1-pyrrolyl)benzohydrazide | N'-(5-bromo-2-oxoindol-3-yl)-2-pyrrol-1-ylbenzohydrazide | SMR000152637 | cid_6006008 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H13BrN4O2 |
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| Mol. Mass. | 409.236 |
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| SMILES | Brc1ccc2=NC(=O)C(NNC(=O)c3ccccc3-n3cccc3)=c2c1 |c:25,t:4| |
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| Structure | 
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