| Reaction Details |
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 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase XIAP |
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| Ligand | BDBM44342 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of Antagonists of IAP-family anti-apoptotic proteins |
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| IC50 | 24100±4000 nM |
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| Citation |  PubChem, PC SAR analysis of Antagonists of IAP-family anti-apoptotic proteins PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| E3 ubiquitin-protein ligase XIAP |
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| Name: | E3 ubiquitin-protein ligase XIAP |
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| Synonyms: | API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 56685.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P98170 |
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| Residue: | 497 |
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| Sequence: | MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT
VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY
LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT
PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE
SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP
SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD
SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK
CPMCYTVITFKQKIFMS
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| BDBM44342 |
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| n/a |
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| Name | BDBM44342 |
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| Synonyms: | MLS-0391063.0001 | cid_44182279 | formic acid;(2S)-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-N-[(2S)-1-oxo-1-(5-quinolinylamino)propan-2-yl]pentanediamide | formic acid;(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]-N-[(2S)-1-oxo-1-(quinolin-5-ylamino)propan-2-yl]pentanediamide | formic acid;(2S)-N-[(1S)-2-keto-1-methyl-2-(5-quinolylamino)ethyl]-2-[[(2S)-2-(methylamino)propanoyl]amino]glutaramide | methanoic acid;(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]-N-[(2S)-1-oxidanylidene-1-(quinolin-5-ylamino)propan-2-yl]pentanediamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28N6O4 |
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| Mol. Mass. | 428.4848 |
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| SMILES | CN[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)Nc1cccc2ncccc12 |
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| Structure | 
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