| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tumor necrosis factor ligand superfamily member 10 |
|---|
| Ligand | BDBM44369 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells. |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells. PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tumor necrosis factor ligand superfamily member 10 |
|---|
| Name: | Tumor necrosis factor ligand superfamily member 10 |
|---|
| Synonyms: | APO2L | TNF10_HUMAN | TNFSF10 | TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 32511.55 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101343 |
|---|
| Residue: | 281 |
|---|
| Sequence: | MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
|
|
|
|---|
| BDBM44369 |
|---|
| n/a |
|---|
| Name | BDBM44369 |
|---|
| Synonyms: | 2-(4-chlorophenyl)-4-(ethylthio)-6-(1-pyrrolidinyl)pyrimidine | 2-(4-chlorophenyl)-4-(ethylthio)-6-pyrrolidino-pyrimidine | 2-(4-chlorophenyl)-4-ethylsulfanyl-6-pyrrolidin-1-yl-pyrimidine | 2-(4-chlorophenyl)-4-ethylsulfanyl-6-pyrrolidin-1-ylpyrimidine | MLS-0390923.0001 | cid_852319 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18ClN3S |
|---|
| Mol. Mass. | 319.852 |
|---|
| SMILES | CCSc1cc(nc(n1)-c1ccc(Cl)cc1)N1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
