| Reaction Details |
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 | Report a problem with these data |
| Target | Tumor necrosis factor ligand superfamily member 10 |
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| Ligand | BDBM44372 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells. |
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| IC50 | 4810±n/a nM |
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| Citation |  PubChem, PC SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tumor necrosis factor ligand superfamily member 10 |
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| Name: | Tumor necrosis factor ligand superfamily member 10 |
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| Synonyms: | APO2L | TNF10_HUMAN | TNFSF10 | TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32511.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101343 |
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| Residue: | 281 |
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| Sequence: | MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
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| BDBM44372 |
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| n/a |
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| Name | BDBM44372 |
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| Synonyms: | 2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthio)-1,3,5-triazine | 2-(dichloromethyl)-4-(4-methylphenyl)-6-methylsulfanyl-1,3,5-triazine | 2-(dichloromethyl)-4-(methylthio)-6-(p-tolyl)-s-triazine | 2-[bis(chloranyl)methyl]-4-(4-methylphenyl)-6-methylsulfanyl-1,3,5-triazine | ML100 | MLS-0092727.0002 | cid_3380841 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H11Cl2N3S |
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| Mol. Mass. | 300.207 |
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| SMILES | CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl |
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| Structure | 
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