| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tumor necrosis factor ligand superfamily member 10 |
|---|
| Ligand | BDBM44373 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells. |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells. PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tumor necrosis factor ligand superfamily member 10 |
|---|
| Name: | Tumor necrosis factor ligand superfamily member 10 |
|---|
| Synonyms: | APO2L | TNF10_HUMAN | TNFSF10 | TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 32511.55 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101343 |
|---|
| Residue: | 281 |
|---|
| Sequence: | MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
|
|
|
|---|
| BDBM44373 |
|---|
| n/a |
|---|
| Name | BDBM44373 |
|---|
| Synonyms: | 2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl-1-pyrrolidin-1-yl-propan-1-one | 2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl-1-pyrrolidin-1-ylpropan-1-one | 2-[[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]thio]-1-(1-pyrrolidinyl)-1-propanone | 2-[[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]thio]-1-pyrrolidino-propan-1-one | MLS-0011658.0001 | cid_3145657 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18F3N3OS |
|---|
| Mol. Mass. | 381.415 |
|---|
| SMILES | CC(Sc1nc(cc(n1)C(F)(F)F)-c1ccccc1)C(=O)N1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
