BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTumor necrosis factor ligand superfamily member 10
LigandBDBM44376
Substrate/Competitorn/a
Meas. Tech.SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells.
IC50>10000±n/a nM
Citation PubChem, PC SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tumor necrosis factor ligand superfamily member 10
Name:Tumor necrosis factor ligand superfamily member 10
Synonyms:APO2L | TNF10_HUMAN | TNFSF10 | TRAIL | tumor necrosis factor (ligand) superfamily, member 10
Type:PROTEIN
Mol. Mass.:32511.55
Organism:Homo sapiens (Human)
Description:EBI_101343
Residue:281
Sequence:
MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM44376
n/a
NameBDBM44376
Synonyms:2-(methylthio)-4,6-diphenyl-1,3,5-triazine | 2-(methylthio)-4,6-diphenyl-s-triazine | 2-methylsulfanyl-4,6-diphenyl-1,3,5-triazine | MLS-0390928.0001 | cid_12909
TypeSmall organic molecule
Emp. Form.C16H13N3S
Mol. Mass.279.36
SMILESCSc1nc(nc(n1)-c1ccccc1)-c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: