| Reaction Details |
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 | Report a problem with these data |
| Target | Ephrin type-A receptor 4 |
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| Ligand | BDBM43212 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists |
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| IC50 | 5080±n/a nM |
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| Citation |  PubChem, PC Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ephrin type-A receptor 4 |
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| Name: | Ephrin type-A receptor 4 |
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| Synonyms: | EPHA4_MOUSE | Eph receptor A4 | Epha4 | Sek | Sek1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 109812.17 |
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| Organism: | Mus musculus |
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| Description: | gi_34328113 |
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| Residue: | 986 |
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| Sequence: | MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM
DEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE
TFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG
FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK
DVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDASCAKCPPHSYSV
WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI
SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVS
KYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE
KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII
GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF
TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT
DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV
IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT
TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG
YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNT
ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAIT
HQNKILSSVQAMRTQMQQMHGRMVPV
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| BDBM43212 |
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| n/a |
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| Name | BDBM43212 |
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| Synonyms: | (5Z)-5-[(2Z)-2-(1-ethyl-3,3-dimethyl-2-indolylidene)ethylidene]-3-propyl-2-sulfanylidene-4-thiazolidinone | (5Z)-5-[(2Z)-2-(1-ethyl-3,3-dimethyl-indol-2-ylidene)ethylidene]-3-propyl-2-sulfanylidene-1,3-thiazolidin-4-one | (5Z)-5-[(2Z)-2-(1-ethyl-3,3-dimethyl-indolin-2-ylidene)ethylidene]-3-propyl-2-thioxo-thiazolidin-4-one | (5Z)-5-[(2Z)-2-(1-ethyl-3,3-dimethylindol-2-ylidene)ethylidene]-3-propyl-2-sulfanylidene-1,3-thiazolidin-4-one | 5-[2-(1-ethyl-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene)ethylidene]-3-propyl-2-thioxo-1,3-thiazolidin-4-one | MLS000544534 | SMR000163634 | cid_11948835 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2OS2 |
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| Mol. Mass. | 372.547 |
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| SMILES | CCCN1C(=S)S\C(=C/C=C2\N(CC)c3ccccc3C2(C)C)C1=O |
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| Structure | 
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