| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor XII |
|---|
| Ligand | BDBM32815 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Factor XIIa 1536 HTS Dose Response Confirmation |
|---|
| IC50 | >50000±0 nM |
|---|
| Citation |  PubChem, PC Factor XIIa 1536 HTS Dose Response Confirmation PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Coagulation factor XII |
|---|
| Name: | Coagulation factor XII |
|---|
| Synonyms: | Beta-factor XIIa part 1 | Beta-factor XIIa part 2 | Carboxylesterase 2 (intestine, liver) | Coagulation factor XII | Coagulation factor XII (FXII) | Coagulation factor XIIa heavy chain | Coagulation factor XIIa light chain | F12 | FA12_HUMAN | Factor XIIa | Factor XIIa (fXIIa) | HAF | Hageman factor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 67810.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00748 |
|---|
| Residue: | 615 |
|---|
| Sequence: | MRALLLLGFLLVSLESTLSIPPWEAPKEHKYKAEEHTVVLTVTGEPCHFPFQYHRQLYHK
CTHKGRPGPQPWCATTPNFDQDQRWGYCLEPKKVKDHCSKHSPCQKGGTCVNMPSGPHCL
CPQHLTGNHCQKEKCFEPQLLRFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQACRT
NPCLHGGRCLEVEGHRLCHCPVGYTGAFCDVDTKASCYDGRGLSYRGLARTTLSGAPCQP
WASEATYRNVTAEQARNWGLGGHAFCRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQTPTQ
AAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCG
QRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAP
EDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSP
YVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS
SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYT
DVAYYLAWIREHTVS
|
|
|
|---|
| BDBM32815 |
|---|
| n/a |
|---|
| Name | BDBM32815 |
|---|
| Synonyms: | 1-benzotriazolyl-[3-(4-methoxyphenyl)-1-phenyl-4-pyrazolyl]methanone | 1-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]carbonyl}-1H-1,2,3-benzotriazole | MLS000534987 | SMR000142423 | benzotriazol-1-yl-[3-(4-methoxyphenyl)-1-phenyl-pyrazol-4-yl]methanone | benzotriazol-1-yl-[3-(4-methoxyphenyl)-1-phenylpyrazol-4-yl]methanone | cid_1326637 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H17N5O2 |
|---|
| Mol. Mass. | 395.4134 |
|---|
| SMILES | COc1ccc(cc1)-c1nn(cc1C(=O)n1nnc2ccccc12)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
