Ki Summary

Reaction Details

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Target

Sphingosine 1-phosphate receptor 2

Ligand

BDBM41599

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA

IC50

362±n/a nM

Citation

PubChem, PC Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA PubChem Bioassay(2008)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Sphingosine 1-phosphate receptor 2

Name:

Sphingosine 1-phosphate receptor 2

Synonyms:

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

38883.16

Organism:

Homo sapiens (Human)

Description:

Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.

Residue:

353

Sequence:

MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV

BDBM41599

n/a

Name

BDBM41599

Synonyms:

(E)-[1-[4-(4-chlorobenzyl)oxyphenyl]-2,5-dimethyl-pyrrol-3-yl]methylene-(1,2,4-triazol-4-yl)amine | 1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethyl-3-pyrrolyl]-N-(1,2,4-triazol-4-yl)methanimine | 1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethyl-pyrrol-3-yl]-N-(1,2,4-triazol-4-yl)methanimine | 1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethylpyrrol-3-yl]-N-(1,2,4-triazol-4-yl)methanimine | MLS000534371 | N-[(1-{4-[(4-chlorobenzyl)oxy]phenyl}-2,5-dimethyl-1H-pyrrol-3-yl)methylene]-4H-1,2,4-triazol-4-amine | SMR000141803 | [1-[4-(4-chlorobenzyl)oxyphenyl]-2,5-dimethyl-pyrrol-3-yl]methylene-(1,2,4-triazol-4-yl)amine | cid_1282232

Type

Small organic molecule

Emp. Form.

C22H20ClN5O

Mol. Mass.

405.88

SMILES

Cc1cc(C=Nn2cnnc2)c(C)n1-c1ccc(OCc2ccc(Cl)cc2)cc1 |w:5.5|

Structure