BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSphingosine 1-phosphate receptor 2
LigandBDBM41609
Substrate/Competitorn/a
Meas. Tech.Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA
IC50 3079±n/a nM
Citation PubChem, PC Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Sphingosine 1-phosphate receptor 2
Name:Sphingosine 1-phosphate receptor 2
Synonyms:EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:38883.16
Organism:Homo sapiens (Human)
Description:Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM41609
n/a
NameBDBM41609
Synonyms:(4,5-dichloro-6-oxopyridazin-1-yl)methyl 4-methylbenzoate | 4-methylbenzoic acid (4,5-dichloro-6-keto-pyridazin-1-yl)methyl ester | 4-methylbenzoic acid (4,5-dichloro-6-oxo-1-pyridazinyl)methyl ester | MLS000546966 | SMR000180164 | [4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]methyl 4-methylbenzoate | [4,5-dichloro-6-oxo-1(6H)-pyridazinyl]methyl 4-methylbenzenecarboxylate | cid_1474465
TypeSmall organic molecule
Emp. Form.C13H10Cl2N2O3
Mol. Mass.313.136
SMILESCc1ccc(cc1)C(=O)OCn1ncc(Cl)c(Cl)c1=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: