| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Ligand | BDBM46133 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP |
|---|
| IC50 | 35000±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Name: | Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 40530.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35236 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
|
|
|
|---|
| BDBM46133 |
|---|
| n/a |
|---|
| Name | BDBM46133 |
|---|
| Synonyms: | (7Z)-3-bromanyl-7-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | (7Z)-3-bromo-7-(2-chlorobenzylidene)thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | (7Z)-3-bromo-7-[(2-chlorophenyl)methylidene]-8-thiazolo[4,5]imidazo[1,2-b]pyridinone | (7Z)-3-bromo-7-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | MLS-0091944.0001 | cid_2258411 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H7BrClN3OS |
|---|
| Mol. Mass. | 392.658 |
|---|
| SMILES | Clc1ccccc1\C=c1/sc2nc3cc(Br)cnc3n2c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
