Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 7 |
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Ligand | BDBM46252 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP |
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IC50 | 4253±n/a nM |
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Citation | PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 7 |
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Name: | Tyrosine-protein phosphatase non-receptor type 7 |
Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
Type: | Protein |
Mol. Mass.: | 40530.79 |
Organism: | Homo sapiens (Human) |
Description: | P35236 |
Residue: | 360 |
Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM46252 |
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n/a |
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Name | BDBM46252 |
Synonyms: | (4E)-2-methoxy-4-[[(phenylmethyl)amino]-sulfanyl-methylidene]cyclohexa-2,5-dien-1-one | (4E)-4-[(benzylamino)-mercapto-methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[(benzylamino)-sulfanylmethylidene]-2-methoxycyclohexa-2,5-dien-1-one | (4E)-4-[mercapto-[(phenylmethyl)amino]methylidene]-2-methoxy-1-cyclohexa-2,5-dienone | MLS-0412121.0001 | cid_20110352 |
Type | Small organic molecule |
Emp. Form. | C15H15NO2S |
Mol. Mass. | 273.35 |
SMILES | COc1cc(ccc1O)C(=S)NCc1ccccc1 |
Structure |
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