| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
|---|
| Ligand | BDBM32280 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. |
|---|
| EC50 | 33670±n/a nM |
|---|
| Citation |  PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Bcl-2-like protein 10 [11-204] |
|---|
| Name: | Bcl-2-like protein 10 [11-204] |
|---|
| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 21981.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_23396469 |
|---|
| Residue: | 194 |
|---|
| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
|
|
|
|---|
| BDBM32280 |
|---|
| n/a |
|---|
| Name | BDBM32280 |
|---|
| Synonyms: | MLS000534769 | N-(4-acetylphenyl)-2,3-bis(2-furanyl)-6-quinoxalinecarboxamide | N-(4-acetylphenyl)-2,3-bis(2-furyl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-di-2-furyl-6-quinoxalinecarboxamide | N-(4-ethanoylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | SMR000142225 | cid_1331726 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H17N3O4 |
|---|
| Mol. Mass. | 423.4202 |
|---|
| SMILES | CC(=O)c1ccc(NC(=O)c2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
