| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bcl-2-like protein 2 |
|---|
| Ligand | BDBM32270 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. |
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| EC50 | 4620±n/a nM |
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| Citation |  PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 2 |
|---|
| Name: | Bcl-2-like protein 2 |
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| Synonyms: | Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271 |
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| Type: | Protein |
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| Mol. Mass.: | 20742.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 193 |
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| Sequence: | MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
GALVTVGAFFASK
|
|
|
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| BDBM32270 |
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| n/a |
|---|
| Name | BDBM32270 |
|---|
| Synonyms: | 6,7-dimethoxy-4-(2-oxolanylmethylamino)-1H-quinazoline-2-thione | 6,7-dimethoxy-4-(oxolan-2-ylmethylamino)-1H-quinazoline-2-thione | 6,7-dimethoxy-4-(tetrahydrofurfurylamino)-1H-quinazoline-2-thione | 6,7-dimethoxy-4-[(tetrahydrofuran-2-ylmethyl)amino]quinazoline-2(1H)-thione | MLS000045008 | SMR000026612 | cid_3243470 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C15H19N3O3S |
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| Mol. Mass. | 321.395 |
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| SMILES | COc1cc2nc(=S)[nH]c(NCC3CCCO3)c2cc1OC |
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| Structure | 
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